A mind-bending love story following Greg who, after recently being divorced and then fired, meets the mysterious Isabel, a woman living on the streets and convinced that the polluted, broken world around them is a computer simulation.
In 2074, when the mob wants to get rid of someone, the target is sent into the past, where a hired gun awaits - someone like Joe - who one day learns the mob wants to 'close the loop' by sending back Joe's future self for assassination.
Dr. John Sarno, a renowned rehabilitative medicine specialist and psychosomatic disorder author, has been battling pain for nearly 50 years, despite the medical establishment's disregard.