Domestic Box Office Results for 2021 Week 43 (3-Day Oct 22 - Oct 24)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| - | Dune | - | Warner Bros. | $41,011,174 | - | 4,125 | - | $9,942 | $41,011,174 | 1 |
| - | Halloween Kills | - | Universal Pictures | $14,450,215 | -70.8% | 3,727 | 22 | $3,877 | $73,055,060 | 2 |
| - | No Time to Die | - | Metro-Goldwyn-Mayer (MGM) | $12,202,368 | -48.7% | 3,807 | -600 | $3,205 | $120,357,453 | 3 |
| - | Venom: Let There Be Carnage | PG-13 | Sony Pictures Entertainment (SPE) | $9,301,908 | -43.6% | 3,513 | -500 | $2,648 | $182,031,539 | 4 |
| - | Ron’s Gone Wrong | PG | 20th Century Studios | $7,300,225 | - | 3,560 | - | $2,051 | $7,300,225 | 1 |
| - | The Addams Family 2 | PG | United Artists Releasing | $4,495,736 | -36.4% | 2,907 | -700 | $1,547 | $48,474,713 | 4 |
| - | The Last Duel | - | 20th Century Studios | $2,066,168 | -56.6% | 3,065 | - | $674 | $8,534,136 | 2 |
| - | Shang-Chi and the Legend of the Ten Rings | PG-13 | Walt Disney Studios Motion Pictures | $2,019,505 | -39.2% | 1,600 | -700 | $1,262 | $220,993,337 | 8 |
| - | The French Dispatch | R | Searchlight Pictures | $1,348,804 | - | 52 | - | $25,939 | $1,348,804 | 1 |
| - | Honsla Rakh | - | Independent | $490,000 | -30.6% | 75 | -25 | $6,533 | $1,196,000 | 2 |
| - | Free Guy | - | 20th Century Studios | $244,514 | -62.1% | 380 | -535 | $643 | $121,240,515 | 11 |
| - | Candyman | R | Universal Pictures | $159,640 | -63.8% | 786 | -226 | $203 | $61,036,865 | 9 |
| - | Lamb | R | A24 | $159,075 | -70.7% | 435 | -430 | $366 | $2,522,098 | 3 |
| - | The Rescue | PG | Greenwich Entertainment | $134,736 | -64.7% | 316 | -245 | $426 | $784,894 | 3 |
| - | Becoming Cousteau | PG-13 | Picturehouse | $116,974 | - | 319 | - | $367 | $116,974 | 1 |
| - | Dear Evan Hansen | PG-13 | Universal Pictures | $114,650 | -69.9% | 489 | -485 | $234 | $14,830,345 | 5 |
| - | Jungle Cruise | PG-13 | Walt Disney Studios Motion Pictures | $61,811 | -43.4% | 145 | -90 | $426 | $116,850,710 | 13 |
| - | Titane | R | NEON | $41,099 | -54.4% | 39 | -73 | $1,054 | $1,409,664 | 4 |
| - | Cry Macho | PG-13 | Warner Bros. | $31,032 | -56.6% | 101 | -134 | $307 | $10,130,249 | 6 |
| - | Mass | PG-13 | Bleecker Street Media | $23,794 | -15.5% | 59 | 22 | $403 | $90,038 | 3 |
| - | Bergman Island | R | IFC Films | $23,776 | -57.5% | 89 | -26 | $267 | $113,257 | 2 |
| - | The Many Saints of Newark | R | Warner Bros. | $23,132 | -86.5% | 102 | -400 | $227 | $7,601,188 | 4 |
| - | After We Fell | R | Vertical Entertainment | $17,567 | -70.6% | 40 | -86 | $439 | $2,164,747 | 7 |
| - | The Eyes of Tammy Faye | PG-13 | Searchlight Pictures | $9,560 | -57.4% | 25 | -30 | $382 | $2,388,551 | 6 |
| - | 13 Fanboy | Other | Independent | $9,538 | - | 22 | - | $434 | $9,538 | 1 |
| - | I’m Your Man | R | Bleecker Street Media | $9,086 | -67.6% | 36 | -67 | $252 | $255,802 | 5 |
| - | The Alpinist | PG-13 | Roadside Attractions | $9,023 | 3.6% | 17 | -5 | $531 | $838,411 | 7 |
| - | The Laws of the Universe: The Age of Elohim | PG | Freestyle Releasing | $8,183 | - | 6 | - | $1,364 | $8,183 | 1 |
| - | Learning to Live Together: The Return of Mad Dogs & Englishmen | - | Abramorama | $8,163 | - | 4 | - | $2,041 | $8,163 | 1 |
| - | Hard Luck Love Song | R | Roadside Attractions | $6,533 | -82.2% | 76 | -96 | $86 | $64,503 | 2 |
| - | Luzzu | - | Kino Lorber | $5,767 | 140.9% | 5 | 4 | $1,153 | $9,466 | 2 |
| - | Golden Voices | - | Music Box Films | $5,558 | 73.0% | 14 | 6 | $397 | $20,558 | 3 |
| - | Minyan | Other | Strand Releasing | $4,988 | - | 1 | - | $4,988 | $4,988 | 1 |
| - | Monster Family 2 | PG | Viva Pictures | $3,954 | -93.1% | 23 | -74 | $172 | $76,417 | 2 |
| - | My Country, My Parents | Other | CMC Pictures | $3,870 | -84.5% | 24 | - | $161 | $161,681 | 3 |
| - | On Broadway | - | Kino Lorber | $3,710 | 550.9% | 5 | 1 | $742 | $78,804 | 9 |
| - | Falling for Figaro | - | IFC Films | $1,586 | 61.2% | 4 | -6 | $397 | $33,373 | 4 |
| - | Wife of a Spy | - | Kino Lorber | $1,307 | -64.6% | 5 | -7 | $261 | $57,731 | 6 |
| - | Old Henry | Other | Shout! Factory | $1,242 | 3.9% | 4 | - | $311 | $40,076 | 4 |
| - | The Lost Leonardo | PG-13 | Sony Pictures Classics | $1,009 | 0.2% | 7 | -1 | $144 | $439,655 | 11 |
| - | Tango Shalom | PG-13 | Vision Films | $996 | -45.4% | 5 | - | $199 | $99,066 | 8 |
| - | Azor | - | MUBI | $505 | -74.2% | 4 | -4 | $126 | $46,678 | 7 |
| - | 12 Mighty Orphans | PG-13 | Sony Pictures Entertainment (SPE) | $229 | -28.4% | 1 | -2 | $229 | $3,689,952 | 20 |
| - | Breathless (2021 Re-release) | TV-14 | Rialto Pictures | $129 | -92.3% | 1 | -2 | $129 | $36,715 | 5 |
| - | Ema | R | Music Box Films | $84 | -61.1% | 1 | - | $84 | $53,177 | 11 |
| - | Summer of 85 | Other | Music Box Films | $44 | - | 1 | 1 | $44 | $71,655 | 11 |
| - | Nine Days | R | Sony Pictures Classics | $41 | -89.6% | 1 | -2 | $41 | $693,941 | 13 |